Betamethasone Impurity 10 CAS 38680-83-0
| CAS No. | 38680-83-0 |
| Molecular Formula | C20H25FO3 |
| Molecular Weight | 332.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.41 g/mol gives Betamethasone Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Betamethasone Impurity 10 (CAS 38680-83-0), a certified reference material (molecular formula C20H25FO3, MW 332.41 g/mol) for analytical method development and quality control.
The molecular framework of Betamethasone Impurity 10 (C20H25FO3) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25FO3 |
| Molecular Weight | 332.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 26 (CAS 98574-03-9)
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- Betamethasone EP Impurity C (CAS 13504-15-9)
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- Betamethasone Impurity 94 (CAS 19784-87-3)
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Recommended Standards
- 2-Cyclohexylethylzinc bromide 0.5 M in Tetrahydrofuran (CAS 82845-20-3)
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- 2,4-Difluoro-N-((1-isopropylpiperidin-4-yl)methyl)benzenesulfonamide (CAS 946233-86-9)
- Oxitropium bromide EP Impurity C (CAS 99571-64-9)
- 5-Bromo-2-(2,4-dichlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1774903-13-7)
- 2-Amino-2-methylbutanenitrile (CAS 4475-95-0)
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- 3-(4,4-Difluoropyrrolidin-2-yl)-5-(trifluoromethyl)-1,2,4-oxadiazole hydrochloride (CAS 2097937-22-7)
- 3-Formyl-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile (CAS 1190309-91-1)
- 8-(3,5-Dimethylphenyl)-8-oxooctanoic acid (CAS 870287-00-6)
- 4-(4,5-Dihydrooxazol-2-yl)-1,2,5-oxadiazol-3-amine (CAS 1431728-34-5)
- 1-Benzyl-3-(4-bromophenyl)urea (CAS 13208-62-3)
- (R)-2-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid (CAS 27025-24-7)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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