(3,4,5-Trimethoxybenzyl)hydrazine hydrochloride CAS 3903-97-7
| CAS No. | 3903-97-7 |
| Molecular Formula | C10H16N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3,4,5-Trimethoxybenzyl)hydrazine hydrochloride is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3,4,5-Trimethoxybenzyl)hydrazine hydrochloride (CAS 3903-97-7) is a high-purity analytical reference standard with the molecular formula C10H16N2O3HCl and a molecular weight of 248.71 g/mol.
The molecular framework of (3,4,5-Trimethoxybenzyl)hydrazine hydrochloride (C10H16N2O3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O3 HCl |
| Molecular Weight | 248.71 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimethoxybenzyl Standards
- 4-Oxo-4-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)butanoic acid (CAS 1010915-59-9)
- 5-Oxo-5-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)pentanoic acid (CAS 1010936-56-7)
- N-(3,4,5-trimethoxybenzyl)cyclopentanamine hydrochloride (CAS 1052525-88-8)
- 1-(3,4,5-Trimethoxybenzyl)-1H-pyrazol-5-amine (CAS 1052547-81-5)
- 2,4,6-Trimethoxybenzyl bromide (CAS 1094663-93-0)
- (3,4,5-Trimethoxybenzyl)hydrazine dihydrochloride (CAS 1260743-55-2)
- 1346598-93-3 3,4,5-Trimethoxybenzyl-13C3 Bromide (CAS 1346598-93-3)
- 1-(3,4,5-Trimethoxybenzyl)piperidin-4-amine dihydrochloride (CAS 1443424-30-3)
Recommended Standards
- Naugard® A (CAS 68412-48-6)
- Cefixime Trihydrate (CAS 125110-14-7)
- 4-Bromo-5-methylindolin-2-one (CAS 1935366-54-3)
- 4-Bromo-2,6-difluoropyridine (CAS 903513-58-6)
- Droxinostat (CAS 99873-43-5)
- 4-Hydroxy-1H-pyrazol-3(2H)-one (CAS 53666-86-7)
- Avanafil Impurity 151 (CAS CATO-C4X-1118151)
- 3-(4-fluorophenyl)-2-(2-pyridyl)oxirane-2-carboxamide (CAS 278610-35-8)
- Methyl 7-oxo-7H-benzo[c]fluorene-6-carboxylate (CAS 200348-34-1)
- Serpent Peptide (CAS 823202-99-9)
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