N-(5-Acetyl-4-phenylthiazol-2-yl)-2-chlorobenzamide CAS 391221-29-7
| CAS No. | 391221-29-7 |
| Molecular Formula | C18H13ClN2O2S |
| Molecular Weight | 356.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(5-Acetyl-4-phenylthiazol-2-yl)-2-chlorobenzamide (CAS 391221-29-7) is a high-purity analytical reference standard with the molecular formula C18H13ClN2O2S and a molecular weight of 356.83 g/mol.
The molecular framework of N-(5-Acetyl-4-phenylthiazol-2-yl)-2-chlorobenzamide (C18H13ClN2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(5-Acetyl-4-phenylthiazol-2-yl)-2-chlorobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClN2O2S |
| Molecular Weight | 356.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- 6-(4-Chlorophenyl)-3-(4-ethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (CAS 211750-08-2)
- Etoricoxib Impurity 44 (CAS 855307-79-8)
- 3-[(4-Chlorobenzenesulfonyl)methyl]-4-(1H-pyrrol-1-yl)benzonitrile (CAS 454473-77-9)
- Etoricoxib Impurity 45 (CAS 855307-80-1)
- N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-((1-(4-methylbenzyl)-1H-imidazol-2-yl)thio)acetamide (CAS 869346-53-2)
- n-(4-Chloro-3-nitrophenyl)-2-((1-methyl-1h-imidazol-2-yl)thio)acetamide (CAS 306730-71-2)
- 3-Ethynyl-2-methylfuran (CAS 1936544-90-9)
- N-(4-Chlorophenyl)-5-phenyl-1,3,4-oxadiazol-2-amine (CAS 917912-30-2)
- 2-(3-Aminopyrrolidin-1-yl)benzamide (CAS 1248724-48-2)
- 4-(2-Chlorobenzyl)piperazin-1-amine (CAS 395662-85-8)
- 2-Chloro-5-fluoro-4-thiocyanatopyrimidine (CAS 112889-53-9)
- 1-(4-(2-Fluorophenyl)thiazol-2-yl)-4-(4-methoxyphenyl)-1H-pyrazol-5-amine (CAS 955963-46-9)
- 7,8-dimethyl-2,3,4,5-tetrahydro-1-benzoxepin-5-one (CAS 32557-51-0)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com