Flunarizine EP Impurity B CAS 39245-25-5
| CAS No. | 39245-25-5 |
| Molecular Formula | C26H27FN2 |
| Molecular Weight | 386.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Flunarizine EP Impurity B (CAS 39245-25-5), a pharmacopoeial impurity reference standard (molecular formula C26H27FN2, MW 386.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Flunarizine EP Impurity B (C26H27FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 386.50 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H27FN2 |
| Molecular Weight | 386.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine Impurity 6 (CAS 768360-45-8)
- Flunarizine EP Impurity C (CAS 90830-31-2)
- Flunarizine EP Impurity D（(Z)-Flunarizine） (CAS 693765-11-6)
- Flunarizine (CAS 52468-60-7)
- Flunarizine impurity 39 (CAS 19422-37-8)
- Flunarizine impurity 34 (CAS CATO-C4X-135734)
- Flunarizine Impurity 7 (CAS 87166-81-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
Recommended Standards
- 7297-95-2 KST-1B8155 {2-[(methoxycarbonyl)amino]imidazo[1,2-a]pyridin-6-yl}(phenyl)sulfoniumolate (CAS 7297-95-2)
- Ala-Leu-Ala-Leu (CAS 84676-48-2)
- Thiol-PEG8-alcohol (CAS 791620-96-7)
- N,N-Dibenzyl-1-(methylsulfonyl)piperidine-3-carboxamide (CAS 1000949-56-3)
- Alprazolam Impurity 16 (CAS CATO-C4X-146016)
- Testosterone Impurity 25 (CAS CATO-C4X-132625)
- Salbutamol EP Impurity E (CAS 24085-03-8)
- (3-Bromo-2-chloro-5-(trifluoromethyl)phenyl)methanol (CAS 2092609-70-4)
- 3-Bromo-1-(1-ethoxyethyl)-4-nitro-1H-pyrazole (CAS 1639858-77-7)
- (4S,7S,12BR)-7-((S)-2-(acetylthio)butanamido)-6-oxo-1,2,3,4,6,7,8,12b-octahydrobenzo[c]pyrido[1,2-a]azepine-4-carboxylic acid (CAS 669764-02-7)
- 4-Isopropyl-N-propylcyclohexan-1-amine (CAS 1341460-64-7)
- 1-Ethyl-5-fluoro-1h-1,3-benzodiazol-2-amine hydrochloride (CAS 1423033-99-1)
- N1,3-dimethyl-N1-((tetrahydro-2H-pyran-4-yl)methyl)benzene-1,4-diamine (CAS 1220016-69-2)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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