Flunarizine impurity 34 CAS CATO-C4X-135734
| CAS No. | CATO-C4X-135734 |
| Molecular Formula | C26H24F2N2O |
| Molecular Weight | 418.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Flunarizine impurity 34 (CAS CATO-C4X-135734, C26H24F2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Flunarizine impurity 34 (C26H24F2N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H24F2N2O |
| Molecular Weight | 418.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine Impurity 7 (CAS 87166-81-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine impurity 53 (CAS CATO-C4X-135753)
- Flunarizine impurity 39 (CAS 19422-37-8)
- Flunarizine EP Impurity C (CAS 90830-31-2)
- Flunarizine EP Impurity D（(Z)-Flunarizine） (CAS 693765-11-6)
- Flunarizine (CAS 52468-60-7)
- Flunarizine Impurity 14 (CAS CATO-C4X-135714)
Recommended Standards
- Decitabine Impurity 45 (CAS CATO-C4X-113745)
- Budesonide Impurity 65 (CAS 2451560-12-4)
- Methanesulfonic acid (4S,5S)-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanesulfonyloxy-methyl]-2,2- dimethyl-[1,3]dioxolan-4-ylmethyl ester (CAS 7115-24-4)
- Propranolol Impurity 13 (CAS 1236367-67-1)
- Ramelteon Impurity 42 (CAS 1053239-38-5)
- Famciclovir Impurity 16 (CAS 452-06-2)
- (R,R)-Formoterol Impurity 97 (CAS CATO-C4X-152552)
- 5-(2,3-Dichlorophenoxymethyl)furan-2-carbaldehyde (CAS 438219-17-1)
- Dopamine Impurity 86 (CAS 74321-37-2)
- 2,5-Difluoro-N-isobutylaniline (CAS 1019559-72-8)
- Methyl 5-hydroxy-4-methoxypicolinate (CAS 188011-51-0)
- 3-Bromo-4-methyl-1H-indole (CAS 1094654-54-2)
- (S)-2-aminooctanoic acid (CAS 116783-26-7)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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