4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one CAS 397-60-4

Purity 97%+In StockPharmaceutical Standards
CAS No.397-60-4
Molecular FormulaC16H10FNO2
Molecular Weight267.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one CAS 397-60-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 267.25 g/mol gives 4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 397-60-4), a certified reference material (molecular formula C16H10FNO2, MW 267.25 g/mol) for analytical method development and quality control.

Structurally, 4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one (C16H10FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 267.25 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H10FNO2
Molecular Weight267.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms1

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