Norepinephrine Impurity 31 CAS 39878-43-8
| CAS No. | 39878-43-8 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Norepinephrine Impurity 31 (CAS 39878-43-8) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClO3 and a molecular weight of 186.59 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Norepinephrine Impurity 31 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
Related Norepinephrine Standards
- Norepinephrine Impurity 10 (CAS 2948-16-5)
- Norepinephrine Impurity 13 (CAS 63704-55-2)
- Norepinephrine Impurity 51 (CAS 73917-81-4)
- Norepinephrine Impurity 158 (CAS CATO-C4X-1514158)
- Norepinephrine Impurity 104 (CAS 5530-29-0)
- Norepinephrine Impurity 101 (CAS 32655-70-2)
- Norepinephrine Impurity 111 (CAS 2947-04-8)
- Norepinephrine impurity 54 (CAS 1932110-67-2)
Recommended Standards
- Noradrenaline EP Impurity E (CAS 99-40-1)
- Glibenclamide Impurity 7 (CAS 3438-16-2)
- p-Hydroxyphenyl chloroacetate (CAS 10421-12-2)
- Adrenaline Impurity 38 (CAS 468721-10-0)
- Esmolol Impurity 62 (CAS CATO-C4X-189162)
- Entecavir Impurity 61 (CAS 1907700-40-6)
- Octreotide Impurity 30 (CAS CATO-C4X-152030)
- 2-(5-Amino-3-fluoropyridin-2-yl)acetic acid (CAS 1214374-22-7)
- (3,4-Dichloro-2-methylphenyl)boronic acid (CAS 957035-17-5)
- 1-[(2,4-Dichlorophenyl)methyl]-5-[4-(prop-2-en-1-yl)-5-sulfanyl-4H-1,2,4-triazol-3-yl]-1,2-dihydropyridin-2-one (CAS 477853-13-7)
- 1,6-Dibromohexane-d12 (CAS 169397-96-0)
- 2-Bromo-3,3,4,4,4-pentafluoro-1-butene (CAS 68318-95-6)
- 5-Methyl-1-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 1281872-46-5)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com