Norepinephrine Impurity 13 CAS 63704-55-2
| CAS No. | 63704-55-2 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Norepinephrine Impurity 13 (CAS 63704-55-2), a pharmacopoeial impurity reference standard (molecular formula C8H7ClO3, MW 186.59 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Norepinephrine Impurity 13 (C8H7ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >80% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
Related Norepinephrine Standards
- Norepinephrine Impurity 10 (CAS 2948-16-5)
- Norepinephrine Impurity 31 (CAS 39878-43-8)
- Norepinephrine Impurity 51 (CAS 73917-81-4)
- Norepinephrine Impurity 158 (CAS CATO-C4X-1514158)
- Norepinephrine Impurity 104 (CAS 5530-29-0)
- Norepinephrine Impurity 101 (CAS 32655-70-2)
- Norepinephrine Impurity 111 (CAS 2947-04-8)
- Norepinephrine impurity 54 (CAS 1932110-67-2)
Recommended Standards
- p-Hydroxyphenyl chloroacetate (CAS 10421-12-2)
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- Glibenclamide Impurity 7 (CAS 3438-16-2)
- Tamsulosin Impurity 70 (CAS CATO-C4X-118770)
- Indometacin Impurity 24 (CAS 99508-25-5)
- Deruxtecan Impurity 3 (CAS CATO-C4X-30573)
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- 3-Bromo-5-methyl-7-propyl-pyrazolo[1,5-a]pyrimidine (CAS 43024-41-5)
- CAS 1104438-47-2 (CAS 1104438-47-2)
- 4-Benzyl-8-bromo-7-fluoro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione (CAS 2361423-97-2)
- Undec-3-yne (CAS 60212-30-8)
- 16-bromohexadecan-1-ol (CAS 59101-28-9)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com