Norepinephrine Impurity 10 CAS 2948-16-5
| CAS No. | 2948-16-5 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Norepinephrine Impurity 10 (CAS 2948-16-5, C8H7ClO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Norepinephrine Impurity 10 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Norepinephrine Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Norepinephrine Standards
- Norepinephrine Impurity 13 (CAS 63704-55-2)
- Norepinephrine Impurity 31 (CAS 39878-43-8)
- Norepinephrine Impurity 51 (CAS 73917-81-4)
- Norepinephrine Impurity 158 (CAS CATO-C4X-1514158)
- Norepinephrine Impurity 104 (CAS 5530-29-0)
- Norepinephrine Impurity 101 (CAS 32655-70-2)
- Norepinephrine Impurity 111 (CAS 2947-04-8)
- Norepinephrine impurity 54 (CAS 1932110-67-2)
Recommended Standards
- p-Hydroxyphenyl chloroacetate (CAS 10421-12-2)
- 3-Chloro-2-methoxybenzoic Acid (CAS 3260-93-3)
- (R)-(-)-2-Chloromandelic acid (CAS 52950-18-2)
- Noradrenaline EP Impurity E (CAS 99-40-1)
- Ramelteon Impurity 4 (CAS CATO-C4X-26224)
- Goserelin Impurity 16 (CAS CATO-C4X-192016)
- Carfilzomib Impurity 97 (CAS CATO-C4X-102297)
- 2-((2-Amino-6-methylpyrimidin-4-yl)amino)-6-methylpyridine-3-thiol (CAS 81587-36-2)
- 4-(3,4-Dichlorophenyl)-2-methylphthalazin-1(2H)-one (CAS 4725-84-2)
- (8s)-10-Oxo-6-thia-9-azaspiro[4.5]decane-8-carboxylic acid (CAS 957012-93-0)
- 5-Bromo-3-(1-(ethylsulfonyl)piperidin-4-yl)-2H-indazole-7-carbonitrile (CAS 872350-26-0)
- (2-(5-Fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)vinyl)boronic acid (CAS 2170835-15-9)
- 1-vinyl-1,2,4-triaZole (CAS 2764-83-2)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com