(E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one CAS 400074-52-4
| CAS No. | 400074-52-4 |
| Molecular Formula | C25H16BrCl2NOS |
| Molecular Weight | 529.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one (CAS 400074-52-4), molecular formula C25H16BrCl2NOS and molecular weight 529.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one (C25H16BrCl2NOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H16BrCl2NOS |
| Molecular Weight | 529.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related E Standards
- N-((4-(4-Bromophenyl)-5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)benzamide (CAS 393839-52-6)
- 2-[4-[Bis(4-bromophenyl)amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850153-24-1)
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Recommended Standards
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- Tris(perfluorophenyl)silane (CAS 20160-40-1)
- N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-5-yl]-2-[2-(2-iodoethoxy)ethoxy]acetamide (CAS 2243016-85-3)
- [2-Amino-2-(furan-2-yl)ethyl]dimethylamine dihydrochloride (CAS 1803572-34-0)
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- 5-Nitro-1-(phenylsulfonyl)indoline (CAS 519056-50-9)
- 5-Bromo-N-(2-ethoxyethyl)-3-nitropyridin-2-amine (CAS 1249309-23-6)
- 3,5-Dibromo-2,4-difluorophenylacetonitrile (CAS 1807054-93-8)
- N-(3-Bromophenyl)-5-methylisoxazole-4-carboxamide (CAS 61643-20-7)
- Methyl (4-fluorophenyl)(4-phenylpiperazin-1-yl)-acetate hydrobromide (CAS 1063629-70-8)
- Methyl 2-[2-(2,2-dicyanoeth-1-en-1-yl)-1H-pyrrol-1-yl]-3,3-dimethylbutanoate (CAS 343373-29-5)
- 2-amino-N,N-dimethyl-4-nitrobenzamide (CAS 1369924-32-2)
- Liraglutide (CAS 204656-20-2)
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