(2E)-1-{2-[(4-bromophenyl)sulfanyl]-4-methylquinolin-3-yl}-3-(4-fluorophenyl)prop-2-en-1-one CAS 400074-53-5
| CAS No. | 400074-53-5 |
| Molecular Formula | C25H17BrFNOS |
| Molecular Weight | 478.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2E)-1-{2-[(4-bromophenyl)sulfanyl]-4-methylquinolin-3-yl}-3-(4-fluorophenyl)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2E)-1-{2-[(4-bromophenyl)sulfanyl]-4-methylquinolin-3-yl}-3-(4-fluorophenyl)prop-2-en-1-one (CAS 400074-53-5) is a high-purity analytical reference standard with the molecular formula C25H17BrFNOS and a molecular weight of 478.38 g/mol.
The molecular framework of (2E)-1-{2-[(4-bromophenyl)sulfanyl]-4-methylquinolin-3-yl}-3-(4-fluorophenyl)prop-2-en-1-one (C25H17BrFNOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H17BrFNOS |
| Molecular Weight | 478.38 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related E Standards
- N-(2-Bromophenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577960-68-0)
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Recommended Standards
- Tert-butyl (S)-4-(6-((5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)amino)pyridin-3-yl)-3-methylpiperazine-1-carboxylate (CAS 1433849-64-9)
- Ethyl 4-(3-bromo-5-ethoxy-4-hydroxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 4529-13-9)
- Tedizolid Impurity 67 (CAS CATO-C4X-105467)
- 5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-8,9-dimethoxy-3-(propan-2-yl)-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1023939-04-9)
- (R)-1-Cyclopentylethan-1-ol (CAS 122382-79-0)
- 2-((1,3-Dioxolan-2-yl)methoxy)benzonitrile (CAS 1443353-73-8)
- 1-((4-Bromo-1,3-dimethyl-1h-pyrazol-5-yl)methyl)-1h-pyrazol-3-amine (CAS 1492671-02-9)
- Glucaric acid calcium salt Tetrahydrate (CAS 5793-89-5)
- Ethyl 3,4-dimethylbenzoate (CAS 33499-44-4)
- 2-(4-(((Cyclopropylmethyl)amino)methyl)piperidin-1-yl)ethanamine (CAS 1353973-19-9)
- 4-Methylumbelliferyl α-L-arabinofuranoside (CAS 77471-44-4)
- 8-Ethyl-2-methylquinolin-4(1H)-one (CAS 62510-41-2)
- Abemaciclib Impurity 68 (CAS 2138499-06-4)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
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