2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide CAS 477330-76-0
| CAS No. | 477330-76-0 |
| Molecular Formula | C22H17BrClN5O2S |
| Molecular Weight | 530.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide (CAS 477330-76-0) is a high-purity analytical reference standard with the molecular formula C22H17BrClN5O2S and a molecular weight of 530.82 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 530.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17BrClN5O2S |
| Molecular Weight | 530.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide (CAS 477330-05-5)
- N-(2-Bromophenyl)-2-((4-(4-chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476484-48-7)
- N-(3-Bromophenyl)-2-((4-(4-chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476484-46-5)
- N-((4-(4-Bromophenyl)-5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)benzamide (CAS 393839-52-6)
- (E)-1-(2-((4-bromophenyl)thio)-4-methylquinolin-3-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one (CAS 400074-52-4)
- 2-[4-[Bis(4-bromophenyl)amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850153-24-1)
- {5-[(4-bromophenyl)sulfanyl]-1-methyl-3-phenyl-1H-pyrazol-4-yl}methyl N-(3-chlorophenyl)carbamate (CAS 318289-28-0)
- N-(4-((4-bromophenyl)sulfonyl)phenyl)-2-chloro-4-(methylsulfonyl)benzamide (CAS 400088-88-2)
Recommended Standards
- (+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane 1,2-bis((2S,5S)-2,5-diphenylphospholan-1-yl)ethane 824395-67-7 (CAS 824395-67-7)
- (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane 1,2-bis((2R,5R)-2,5-diphenylphospholan-1-yl)ethane 528565-79-9 (CAS 528565-79-9)
- Diisotridecyl phthalate (CAS 27253-26-5)
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- Nintedanib Impurity 163 (CAS CATO-C4X-1814163)
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- 3,5-Difluoro-4-iodo-pyridine-2-carbonitrile (CAS 1350648-40-6)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1258402-42-4)
- 3,5-Dichloro-4-formylphenyl acetate (CAS 1582770-02-2)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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