5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile CAS 400084-55-1

Purity 97%+In StockPharmaceutical Standards
CAS No.400084-55-1
Molecular FormulaC9H6ClN5
Molecular Weight219.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile CAS 400084-55-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 219.63 g/mol gives 5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 400084-55-1), molecular formula C9H6ClN5 and molecular weight 219.63 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Amino-1-(6-chloropyridin-2-yl)-1H-pyrazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H6ClN5
Molecular Weight219.63 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms5

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