Olaparib CAS 763113-22-0
| CAS No. | 763113-22-0 |
| Molecular Formula | C24H23FN4O3 |
| Molecular Weight | 434.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Olaparib (CAS 763113-22-0), a certified reference material (molecular formula C24H23FN4O3, MW 434.46 g/mol) for analytical method development and quality control.
The molecular framework of Olaparib (C24H23FN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H23FN4O3 |
| Molecular Weight | 434.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib Impurity 122 (CAS CATO-C4X-1135122)
- Olaparib Impurity 123 (CAS CATO-C4X-1135123)
- Olaparib Impurity 124 (CAS CATO-C4X-1135124)
- Olaparib Impurity 125 (CAS CATO-C4X-1135125)
- Olaparib Impurity 126 (CAS CATO-C4X-1135126)
- Olaparib Impurity 127 (CAS CATO-C4X-1135127)
- Olaparib Impurity 8 (CAS CATO-C4X-11358)
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
Recommended Standards
- Phenyl 1-Thio-β-lactoside (CAS 5329-58-8)
- Methyl 3-(2-(2-((4-methoxyphenyl)amino)-2-oxoacetyl)-1H-pyrrol-1-yl)benzo[b]thiophene-2-carboxylate (CAS 477872-77-8)
- Adalimumab (CAS 331731-18-1)
- 1-(6-Ethylbenzo[d]thiazol-2-yl)-5-(furan-2-yl)-3-hydroxy-4-(5-methylfuran-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 618416-45-8)
- 2-(2-Chloro-4,5-dimethylphenoxy)acetamide (CAS 1706463-28-6)
- 3-Chloro-2-(difluoromethyl)pyridine (CAS 1805301-63-6)
- 2-chloro-1,3-benzothiazol-7-amine (CAS 1782641-10-4)
- [1,2,4]Triazolo[1,5-a]pyridine-7-methanamine (CAS 1313726-30-5)
- 25081-39-4 Benzoic acid, 3,5-dimethyl-, methyl ester Methyl 3,5-dimethylbenzoate (CAS 25081-39-4)
- Benzyl-PEG9-Ots (CAS 393517-91-4)
- 2-(Chloromethyl)-3-fluorobenzonitrile (CAS 1260814-51-4)
- 2,3,5,6-Tetrafluoro-4-(phenylsulfonyl)pyridine (CAS 23449-67-4)
- 2-bromo-7-fluoro-tetralin-1-one (CAS 93753-94-7)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com