3-Fluoro-4-nitrobenzoic acid CAS 403-21-4
| CAS No. | 403-21-4 |
| Molecular Formula | C7H4FNO4 |
| Molecular Weight | 185.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Fluoro-4-nitrobenzoic acid (CAS 403-21-4), a certified reference material (molecular formula C7H4FNO4, MW 185.11 g/mol) for analytical method development and quality control.
Based on its molecular formula C7H4FNO4, 3-Fluoro-4-nitrobenzoic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 185.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluoro-4-nitrobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4FNO4 |
| Molecular Weight | 185.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
- 5-Fluoro-6-nitrobenzo[d][1,3]dioxole (CAS 1366234-02-7)
- 3-Fluoro-5-nitrobenzoic Acid (CAS 14027-75-9)
- 6-Fluoro-3-nitropicolinamide (CAS 171178-31-7)
- 2-Fluoro-3-nitrobenzoic Acid (CAS 317-46-4)
- 2-Fluoro-4-hydroxy-5-nitrobenzaldehyde (CAS 394-34-3)
- 2-Fluoro-6-nitrobenzoic Acid (CAS 385-02-4)
- 3-Fluoro-2-hydroxy-5-nitrobenzaldehyde (CAS 2923-99-1)
Recommended Standards
- 4-Fluoro-3-nitrobenzoic acid (CAS 453-71-4)
- Enzalutamide Impurity 24 (CAS 403-24-7)
- 6-Fluoro-2-hydroxy-3-nitrobenzaldehyde (CAS 38225-97-7)
- Bis(cyclopentadienyl)manganese (CAS 1271-27-8)
- 6-{[(4-Ethylphenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 434907-95-6)
- 1-(Oxetan-3-yl)piperidin-4-amine (CAS 1228948-07-9)
- 2-Chloro-4-(3,4,5-trimethoxyphenyl)nicotinonitrile (CAS 1281804-21-4)
- 4-Chloro-1H-imidazo[4,5-d]pyridazine (CAS 1083181-53-6)
- 4-methyloxepane-4-carboxylic acid (CAS 2299045-56-8)
- n,n-Diethyl-4-[(methylamino)methyl]aniline (CAS 863646-17-7)
- 2-((1H-1,2,4- Triazol-1-yl)methyl)cycloheptanone (CAS 313276-51-6)
- (3-Chlorophenyl)(6-chloropyridin-3-yl)methanone (CAS 1187168-11-1)
- (S)-tert-Butyl 3-((2-chloropyrimidin-4-yl)amino)pyrrolidine-1-carboxylate (CAS 1146159-96-7)
- Peptide 438 (CAS CATO-CPTD788438)
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