Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate CAS 403841-76-9
| CAS No. | 403841-76-9 |
| Molecular Formula | C13H9ClN2O2 |
| Molecular Weight | 260.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 260.68 g/mol gives Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate (CAS 403841-76-9), a certified reference material (molecular formula C13H9ClN2O2, MW 260.68 g/mol) for analytical method development and quality control.
Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate (C13H9ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN2O2 |
| Molecular Weight | 260.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
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- Methyl 6-chloro-9H-pyrido[3,4-b]indole-3-carboxylate (CAS 110522-03-7)
- 3-Chloro-N-(4-cyano-1-methyl-1H-pyrazol-5-yl)benzamide (CAS 1171323-74-2)
- 2-(4-Chloro-1H-pyrazol-1-yl)-N-(4-cyanophenyl)acetamide (CAS 1178331-17-3)
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Recommended Standards
- Ethyl 4-chloro-3-cyanoquinoline-6-carboxylate (CAS 872577-51-0)
- Ethyl 4-chloro-8-cyanoquinoline-3-carboxylate (CAS 77173-67-2)
- 9-Benzyl-2-chloro-9H-purin-6-ol (CAS 95194-86-8)
- methyl 1-(3-chloro-2-cyanophenyl)-1H-pyrrole-2-carboxylate (CAS 866042-56-0)
- Magnesium iodide (CAS 10377-58-9)
- N-(2-Chlorophenyl)-5-(methylsulfonyl)picolinamide (CAS 1380672-71-8)
- N,N-dimethyltetradecan-1-amine (CAS 112-75-4)
- (R)-(2-Amino-4-methyl-pentyl)-carbamic acid tert-butyl ester (CAS 1218944-36-5)
- 2-Iodo-3-methyl-5-(trifluoromethoxy)phenol (CAS 2383402-88-6)
- 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluorodecanebis(imidamide) (CAS 865-94-1)
- 1-{7-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}ethan-1-amine (CAS 1367942-44-6)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-3-(2,6-dichlorobenzyl)-2-methylpyridin-4(1H)-one (CAS 339017-48-0)
- Betahistine impurity 32 (CAS CATO-C4X-183832)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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