2-Chloro-5-fluoro-4-phenoxypyrimidine CAS 40423-66-3
| CAS No. | 40423-66-3 |
| Molecular Formula | C10H6ClFN2O |
| Molecular Weight | 224.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-fluoro-4-phenoxypyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-5-fluoro-4-phenoxypyrimidine (CAS 40423-66-3) is a high-purity analytical reference standard with the molecular formula C10H6ClFN2O and a molecular weight of 224.62 g/mol.
2-Chloro-5-fluoro-4-phenoxypyrimidine (C10H6ClFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClFN2O |
| Molecular Weight | 224.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-6-(3-fluorophenoxy)pyrimidine (CAS 1017067-02-5)
- 2-chloro-4-(4-fluorophenoxy)pyrimidine (CAS 1090835-72-5)
- 5-(3-chloro-4-fluorophenyl)-1,2,4-triazin-3-amine (CAS 1094231-67-0)
- 5-(3-Chloro-4-fluorophenyl)pyrimidin-2-ol (CAS 1111107-97-1)
- 5-(3-Chloro-5-fluorophenyl)pyrimidin-2-ol (CAS 1111113-16-6)
- 4-(4-Chloro-1h-pyrazol-1-yl)-3-fluorobenzaldehyde (CAS 1178311-05-1)
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-fluorobenzaldehyde (CAS 1183264-59-6)
- 2-Chloro-4-(3-fluorophenoxy)pyrimidine (CAS 1242240-84-1)
Recommended Standards
- 1-(4-Chloro-2-fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 2379321-65-8)
- 2-Chloro-6-(3-fluorophenoxy)pyrazine (CAS 894416-95-6)
- 5-(4-Chloro-2-fluorophenyl)pyrazin-2(1H)-one (CAS 1933577-81-1)
- 4-Chloro-5-(2-fluoropyridin-3-yl)-1H-pyrrole-3-carbaldehyde (CAS 928325-27-3)
- 2-Bromo-3-(difluoromethyl)-5-methoxy-6-(trifluoromethyl)pyridine (CAS 1805164-26-4)
- 2-((4-(N-(4-ethoxyphenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 433315-09-4)
- Fukinolic acid (CAS 50982-40-6)
- N-Boc-1-cyclopropyl-2-propyn-1-amine (CAS 1914943-50-2)
- Dyclonine Impurity 4 (CAS CATO-C4X-18814)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((1-(2-methoxyphenyl)-5-nitro-1H-benzo[d]imidazol-2-yl)thio)acetamide (CAS 764699-54-9)
- 6-Bromo-4-hydroxyquinoline-8-carbonitrile (CAS 1160474-80-5)
- 1-methyl-2-oxoindoline-5-sulfonyl chloride (CAS 166883-20-1)
- (S)-Benzyl (1-amino-2-oxopyrrolidin-3-yl)carbamate (CAS 801298-99-7)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
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