N-(4-(Trifluoromethyl)benzyl)aniline CAS 405-80-1
| CAS No. | 405-80-1 |
| Molecular Formula | C14H12F3N |
| Molecular Weight | 251.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(4-(Trifluoromethyl)benzyl)aniline (CAS 405-80-1) is a high-purity analytical reference standard with the molecular formula C14H12F3N and a molecular weight of 251.25 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, N-(4-(Trifluoromethyl)benzyl)aniline is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 251.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12F3N |
| Molecular Weight | 251.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 4-Methyl-3-[4-(trifluoromethyl)phenyl]aniline (CAS 1414870-58-8)
- Phenyl(4-(trifluoromethyl)phenyl)methanamine (CAS 154233-38-2)
- (2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methanamine (CAS 472964-38-8)
- (2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-20-8)
- (3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanamine (CAS 946714-18-7)
- (3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methanamine (CAS 472964-39-9)
- (3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-21-9)
- (4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanamine (CAS 771582-31-1)
Recommended Standards
- Chlorpromazine Related Compound 3 (CAS 20650-07-1)
- N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-Fluorobenzamide (CAS 77694-31-6)
- Benzyl 3-fluoro-4-oxopiperidine-1-carboxylate (CAS 845256-59-9)
- N-benzyl-2-(trifluoromethyl)aniline (CAS 852635-14-4)
- Alcohol C<SUB>2</SUB>F<SUB>5</SUB>-Togni reagent (CAS 1640118-52-0)
- (S)-4-chloro-3-(pyrrolidin-2-yl)benzoic acid (CAS 1213450-23-7)
- 2-[3-(aminomethyl)phenoxy]acetic acid hydrochloride (CAS 33321-39-0)
- Isophthalic acid-carboxy-<SUP>13</SUP>C<SUB>2</SUB> (CAS 112043-90-0)
- 4-Oxo-2-(4-phenoxypiperazin-1-yl)-4-[4-(propan-2-yl)phenyl]butanoic acid (CAS 329777-65-3)
- 1,1-Difluoro-3-phenylpropan-2-ol (CAS 145299-86-1)
- 5-(Furan-2-yl)pyrimidin-2-ol (CAS 1111103-78-6)
- 6-(4-(Methoxymethoxy)benzamido)imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1662687-79-7)
- 3-(3,5-Dimethyl-4-((methylamino)methyl)-1h-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 956437-74-4)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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