N-Benzyl-4-(trifluoromethyl)aniline CAS 405-81-2
| CAS No. | 405-81-2 |
| Molecular Formula | C14H12F3N |
| Molecular Weight | 251.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H12F3N, N-Benzyl-4-(trifluoromethyl)aniline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-Benzyl-4-(trifluoromethyl)aniline (CAS 405-81-2) is a high-purity analytical reference standard with the molecular formula C14H12F3N and a molecular weight of 251.25 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-Benzyl-4-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12F3N |
| Molecular Weight | 251.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-benzyl-2-(trifluoromethyl)aniline (CAS 852635-14-4)
- Phenyl(3-(trifluoromethyl)phenyl)methanamine (CAS 70428-92-1)
- N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-Fluorobenzamide (CAS 77694-31-6)
- tert-Butyl 4-(Trifluoromethyl)-5,6-dihydropyridine-1(2H)-carboxylate (CAS 291289-18-4)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
- Isoquinoline N-Oxide (CAS 1532-72-5)
- 3-(Hydroxymethyl)benzofuran (CAS 4687-23-4)
- (3-Aminopyridin-2-yl)dimethylphosphine oxide (CAS 2361949-70-2)
- 1-(2-Bromo-4-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1086599-53-2)
- 2-Hydroxy-3-phenoxypropanamide (CAS 710-12-3)
- 7721-01-9 Tantalum(V) chloride MFCD00011253 Tantalum chloride Tantalum chloride (TaCl5) Tantalum (V) chloride (CAS 7721-01-9)
- 1-(3-Bromophenyl)-3-phenylpropan-1-one (CAS 866821-66-1)
- Ribociclib Impurity 25 (CAS CATO-C4X-310025)
- Peptide Impurity 15 (CAS 1227750-69-7)
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