4-chloro-6-(2-fluorobenzyl)pyrimidine CAS 405930-77-0

Description

Compared with other compounds in its class, the molecular weight of 222.65 g/mol gives 4-chloro-6-(2-fluorobenzyl)pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-chloro-6-(2-fluorobenzyl)pyrimidine (CAS 405930-77-0) is a high-purity analytical reference standard with the molecular formula C11H8ClFN2 and a molecular weight of 222.65 g/mol.

4-chloro-6-(2-fluorobenzyl)pyrimidine (C11H8ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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