4-Chloro-6-(2,6-difluorophenyl)pyrimidine CAS 405930-78-1

Purity 97%+In StockPharmaceutical Standards
CAS No.405930-78-1
Molecular FormulaC10H5ClF2N2
Molecular Weight226.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-6-(2,6-difluorophenyl)pyrimidine CAS 405930-78-1 chemical structure

Description

The occurrence of 4-Chloro-6-(2,6-difluorophenyl)pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-6-(2,6-difluorophenyl)pyrimidine (CAS 405930-78-1) is a high-purity analytical reference standard with the molecular formula C10H5ClF2N2 and a molecular weight of 226.61 g/mol.

Based on its molecular formula C10H5ClF2N2, 4-Chloro-6-(2,6-difluorophenyl)pyrimidine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-6-(2,6-difluorophenyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H5ClF2N2
Molecular Weight226.61 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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