Promethazine Impurity 70 CAS 409314-72-3(free base)

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.409314-72-3(free base)
Molecular FormulaC4H10ClN
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Promethazine Impurity 70 CAS 409314-72-3(free base) chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

As a process- or degradation-related impurity, Promethazine Impurity 70 (CAS 409314-72-3(free base), C4H10ClNHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Based on its molecular formula C4H10ClNHCl, Promethazine Impurity 70 contains chlorine substitution; these features give the compound characteristic molecular-ion distribution patterns in mass spectrometry. The molecular weight of 144.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC4H10ClN HCl
Molecular Weight144.04 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)-1.0
Halogen ContentCl-containing
Nitrogen Atoms1

Related Promethazine Standards

Recommended Standards

Why CATO?