Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) CAS 4101-81-9

Description

Compared with other compounds in its class, the molecular weight of 184.21 g/mol gives Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) (CAS 4101-81-9), a pharmacopoeial impurity reference standard (molecular formula C8H8O3S, MW 184.21 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) (C8H8O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com