Misoprostol EP Impurity F CAS 41138-61-8
| CAS No. | 41138-61-8 |
| Molecular Formula | C13H20O4 |
| Molecular Weight | 240.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.30 g/mol gives Misoprostol EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Misoprostol EP Impurity F (CAS 41138-61-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20O4 and a molecular weight of 240.30 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Misoprostol EP Impurity F is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 240.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Misoprostol EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20O4 |
| Molecular Weight | 240.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
Related Misoprostol Standards
- Misoprostol EP Impurity F (CAS 40098-26-8)
- Misoprostol Impurity F (CAS 42038-75-5)
- 8-iso Misoprostol (CAS 1256643-55-6)
- Misoprostol EP Impurity D (Mixture of E/Z-Isomers) (CAS 1331639-92-9)
- Misoprostol EP Impurity D (Mixture of Enantiomers) (CAS 1788085-79-9)
- Misoprostol EP Impurity C (CAS 58682-86-3)
- Misoprostol Acid (CAS 112137-89-0)
- Misoprostol Acid (Mixture of Diastereomers) (CAS 66792-31-2)
Recommended Standards
- Tiotropium EP Impurity A (CAS 4746-63-8)
- Acetylcysteine EP Impurity A (CAS 56-89-3)
- Perindopril EP Impurity J (CAS 685523-06-2)
- Oseltamivir Impurity 241 (CAS CATO-C4X-1720241)
- Atrasentan Impurity 60 (CAS 1072963-94-0)
- Minoxidil Impurity 60 (CAS CATO-C4X-170060)
- Aminocaproic Acid Impurity 4 (CAS 19837-09-3)
- 1-(2-Fluorophenyl)-3-hydroxy-3-methylurea (CAS 56935-02-5)
- 6-Bromo-1,4-dichloroisoquinoline (CAS 1254514-12-9)
- 4'-Acetyl-[1,1'-biphenyl]-4-carbonitrile (CAS 59211-64-2)
- 2-(3-Ethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3(2H)-one (CAS 1189423-81-1)
- N-(2-((6-Phenylthieno[2,3-d]pyrimidin-4-yl)amino)ethyl)acetamide (CAS 924371-24-4)
- Haloperidol Impurity 38 HCl (CAS 52669-92-8 (free base))
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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