2-Chloro-2-(4-chlorophenyl)ethan-1-ol CAS 41252-79-3
| CAS No. | 41252-79-3 |
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-2-(4-chlorophenyl)ethan-1-ol.
CATO supplies 2-Chloro-2-(4-chlorophenyl)ethan-1-ol (CAS 41252-79-3), a certified reference material (molecular formula C8H8Cl2O, MW 191.05 g/mol) for analytical method development and quality control.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-Chloro-2-(4-chlorophenyl)ethan-1-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 1-chloro-2-(chloromethyl)-4-methoxybenzene (CAS 101079-83-8)
- 2-Chloro-4-methoxybenzyl chloride (CAS 101080-63-1)
- 2-Chloro-1-(3-chloro-phenyl)-ethanol (CAS 106262-93-5)
- 1-Chloro-4-(2-chloroethoxy)benzene (CAS 13001-28-0)
- 2-Chloro-4-(chloromethyl)-1-methoxybenzene (CAS 13719-57-8)
- 1-Chloro-4-(chloromethyl)-2-methoxybenzene (CAS 13726-18-6)
- (R)-2-chloro-1-(3-chlorophenyl)ethanol (CAS 142763-10-8)
- (S)-2-Chloro-1-(3-chlorophenyl)ethanol (CAS 174699-78-6)
Recommended Standards
- 2-Chloro-2-(3-chlorophenyl)ethan-1-ol (CAS 886365-85-1)
- 3,4-Dichlorobenzeneethanol (CAS 35364-79-5)
- 2-chloro-1-(chloromethyl)-3-methoxybenzene (CAS 52516-44-6)
- 4-(Dichloromethyl)-4-methylcyclohexa-2,5-dien-1-one (CAS 6611-78-5)
- 3-Methyl-3-phenyl-3H-indol-2-amine (CAS 61352-06-5)
- 3-Amino-5-(1H-indol-5-yl)-4-methylpenta-2,4-diene-1,1,1-tricarbonitrile (CAS 134036-53-6)
- 5-Bromo-2-(2-hydroxyethoxy)pyridin-3-ol (CAS 1261365-48-3)
- 2-(3-Methoxy-4-(pentyloxy)phenyl)-1H-imidazo[4,5-b]phenazine (CAS 114991-96-7)
- Diphenyl(vinyl)phosphine oxide (CAS 2096-78-8)
- 1-(4-Amino-5-bromopyridin-3-yl)ethan-1-one (CAS 1393551-05-7)
- Lemborexant Impurity 85 (CAS CATO-C4X-304285)
- 5,7-Dibromo-4-nitro-2H-indazole (CAS 1427460-60-3)
- Methyl 6-(1,1-difluoroethyl)picolinate (CAS 1446508-53-7)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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