2-chloro-1-(chloromethyl)-3-methoxybenzene CAS 52516-44-6
| CAS No. | 52516-44-6 |
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-chloro-1-(chloromethyl)-3-methoxybenzene (CAS 52516-44-6) is a high-purity analytical reference standard with the molecular formula C8H8Cl2O and a molecular weight of 191.05 g/mol.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-chloro-1-(chloromethyl)-3-methoxybenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-chloro-1-(chloromethyl)-3-methoxybenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
Related chloro Standards
- 1-chloro-2-(chloromethyl)-4-methoxybenzene (CAS 101079-83-8)
- 2-Chloro-4-methoxybenzyl chloride (CAS 101080-63-1)
- 2-Chloro-1-(3-chloro-phenyl)-ethanol (CAS 106262-93-5)
- 1-Chloro-4-(2-chloroethoxy)benzene (CAS 13001-28-0)
- 2-Chloro-4-(chloromethyl)-1-methoxybenzene (CAS 13719-57-8)
- 1-Chloro-4-(chloromethyl)-2-methoxybenzene (CAS 13726-18-6)
- (R)-2-chloro-1-(3-chlorophenyl)ethanol (CAS 142763-10-8)
- (S)-2-Chloro-1-(3-chlorophenyl)ethanol (CAS 174699-78-6)
Recommended Standards
- 2-Chloro-1-(4-chlorophenyl)ethanol (CAS 6378-66-1)
- 2-Chloro-2-(3-chlorophenyl)ethan-1-ol (CAS 886365-85-1)
- 2,6-Dichlorophenethyl Alcohol (CAS 30595-79-0)
- 2-Chloro-2-(4-chlorophenyl)ethan-1-ol (CAS 41252-79-3)
- 2-Chloro-6-(4-chlorophenyl)-4-methylnicotinonitrile (CAS 943115-07-9)
- 6-Chloro-N-(piperidin-4-yl)pyrimidin-4-amine (CAS 945896-24-2)
- Octahydropentalen-2-amine hydrochloride (CAS 2408971-51-5)
- 2,5-Dichloro-8-methylquinoline-4-carboxylic acid (CAS 1267302-08-8)
- [2-(Acetylamino)phenyl](oxo)acetic acid (CAS 32375-61-4)
- Demelverine (CAS 13977-33-8)
- 7-Amino-4-bromo-2-methyl-2,3-dihydro-isoindol-1-one (CAS 1257996-53-4)
- 2,2'-(Cyclopentane-1,1-diyl)diacetic Acid (CAS 16713-66-9)
- Ethyl 4-chloro-7-methylquinoline-3-carboxylate (CAS 50593-19-6)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com