Latanoprost EP Impurity H CAS 41639-83-2
| CAS No. | 41639-83-2 |
| Molecular Formula | C23H34O5 |
| Molecular Weight | 390.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 390.51 g/mol gives Latanoprost EP Impurity H distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Latanoprost EP Impurity H (CAS 41639-83-2) is a certified pharmaceutical impurity reference standard with the molecular formula C23H34O5 and a molecular weight of 390.51 g/mol.
Latanoprost EP Impurity H (C23H34O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Latanoprost EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H34O5 |
| Molecular Weight | 390.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
Related Latanoprost Standards
- (15S)-Latanoprost Acid (CAS 41639-84-3)
- Trans-Latanoprost Acid (CAS 903549-49-5)
- Latanoprost Impurity 29 (CAS CATO-C4X-194129)
- Latanoprost EP Impurity H-D4 (CAS 1224443-47-3)
- Latanoprost EP Impurity G (CAS 913258-31-8)
- Latanoprost Impurity 27 (CAS CATO-C4X-194127)
- 2-Nor Latanoprost (CAS CATO-C4X-19414)
- Latanoprost Impurity 30 (CAS CATO-C4X-194130)
Recommended Standards
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- Sildenafil Impurity 268 (CAS CATO-C4X-1128268)
- Atogepant Impurity 76 (CAS CATO-C4X-328576)
- Zidovudine Impurity N6 (CAS 32189-36-9)
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