5-(4-Chlorobenzamido)-4-cyano-N,N-diethyl-3-methylthiophene-2-carboxamide CAS 419558-74-0
| CAS No. | 419558-74-0 |
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorobenzamido)-4-cyano-N,N-diethyl-3-methylthiophene-2-carboxamide (CAS 419558-74-0), molecular formula C18H18ClN3O2S and molecular weight 375.87 g/mol, is a CATO reference standard with documented purity and traceability.
5-(4-Chlorobenzamido)-4-cyano-N,N-diethyl-3-methylthiophene-2-carboxamide (C18H18ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-Chlorobenzamido)-4-cyano-N,N-diethyl-3-methylthiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorobenzamido Standards
- 3-(4-Chlorobenzamido)-4-ethoxybenzenesulfonyl chloride (CAS 680618-29-5)
- 5-(4-Chlorobenzamido)-2-ethoxybenzenesulfonyl chloride (CAS 680617-88-3)
- Ethyl 2-(2-chlorobenzamido)-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 331760-66-8)
- Ethyl 2-(4-chlorobenzamido)-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 299962-45-1)
- Ethyl 2-(2-chlorobenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate (CAS 312949-43-2)
- (R)-2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid (CAS 111911-90-1)
- Ethyl 2-(2-chlorobenzamido)-4-phenylthiophene-3-carboxylate (CAS 331760-72-6)
- Ethyl 2-(4-chlorobenzamido)-4-phenylthiophene-3-carboxylate (CAS 77261-20-2)
Recommended Standards
- 5-(4-Chloro-2-methylphenoxymethyl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 748793-44-4)
- 5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide (CAS 732260-56-9)
- 4-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-1H-indole (CAS 256458-64-7)
- Methyl 2-(4-chlorophenyl)-3-(4-methylbenzoyl)thiazolidine-4-carboxylate (CAS 477768-31-3)
- 2-(Morpholin-4-yl)-1-(1,3-thiazol-2-yl)ethan-1-one hydrochloride (CAS 1417794-40-1)
- (E)-4-(3-(thiophen-2-yl)acryloyl)phenyl 4-bromobenzenesulfonate (CAS 297150-18-6)
- Ethyl 2-(2-ethyl-1H-imidazol-1-yl)acetate (CAS 934172-26-6)
- 3-Bromo-6-((4-hydroxypiperidin-4-yl)methyl)-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS 2196245-70-0)
- Reduced beta-nicotinamide adenine dinucleotide tetracyclohexyl ammonium phosphate salt (CAS 100929-71-3)
- Methyl 5-amino-2,3-bithiophene-4-carboxylate (CAS 444907-56-6)
- Sugammadex Impurity 86 (CAS CATO-C4X-190686)
- (2S,6S)-2-Methyl-6-undecylpiperidine (CAS 35285-25-7)
- 9-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine (CAS 939759-18-9)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com