Propranolol Impurity 17 CAS 4199-10-4
| CAS No. | 4199-10-4 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Propranolol Impurity 17 (CAS 4199-10-4), a pharmacopoeial impurity reference standard (molecular formula C16H21NO2HCl, MW 295.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H21NO2HCl, Propranolol Impurity 17 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 295.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Propranolol Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 HCl |
| Molecular Weight | 295.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Propranolol Standards
- Propranolol Chloro Impurity (CAS 112805-69-3)
- Propranolol Impurity 13 (CAS 1236367-67-1)
- Nor Propranolol-d (CAS 1246819-85-1)
- Propranolol sulfate (CAS 125651-21-0)
- R-Propranolol HCl (CAS 13071-11-9)
- Propranolol Impurity 5 (CAS 132005-35-7)
- Propranolol Impurity 12 (CAS 13917-61-8)
- D7-Propranolol hydrochloride (CAS 1613439-56-7)
Recommended Standards
- Voriconazole Impurity 10 (CAS 239807-03-5)
- Tirofiban Impurity 43 (CAS CATO-C4X-125443)
- Sacubitril impurity 9 (CAS CATO-C4X-28099)
- Brivaracetam Impurity 159 (CAS CATO-C4X-2007159)
- 3-Chloro-4-iodo-6-methoxy-1H-indazole (CAS 887570-02-7)
- 6-Methoxyquinoline-3-carboxamide (CAS 71083-30-2)
- Nalmefene Impurity 17 (CAS CATO-C4X-126817)
- 1-(2,4-Dichlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 102996-38-3)
- 6-Chloro-8-methyl-3-phenylquinolin-2-ol (CAS 1031928-31-0)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com