Palonosetron Impurity 28 CAS 4242-18-6
| CAS No. | 4242-18-6 |
| Molecular Formula | C11H12O2 |
| Molecular Weight | 176.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Palonosetron Impurity 28 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Palonosetron Impurity 28 (CAS 4242-18-6, C11H12O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Palonosetron Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12O2 |
| Molecular Weight | 176.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Palonosetron Standards
- Palonosetron Impurity 24 (CAS 83721-32-8)
- Palonosetron Impurity 25 (CAS 23357-47-3)
- Palonosetron Impurity 29 (CAS 85977-52-2)
- Palonosetron Impurity 20 (CAS 98841-72-6)
- Palonosetron Impurity 27 (CAS 86-55-5)
- Palonosetron Impurity 19 (CAS 66377-63-7)
- Palonosetron Impurity 18 (CAS 91245-72-6)
- Palonosetron Impurity 46 (CAS CATO-C4X-110546)
Recommended Standards
- Empagliflozin Impurity 86 (CAS CATO-C4X-106586)
- Agomelatine Impurity 16 (CAS 6836-19-7)
- Empagliflozin Impurity 85 (CAS CATO-C4X-106585)
- Roxithromycin impurity 29 (CAS CATO-C4X-130329)
- Riociguat Impurity 40 (CAS CATO-C4X-174940)
- Cloxacillin Impurity 39 (CAS CATO-C4X-159739)
- Ertugliflozin impurity 27 (CAS 1210344-58-3)
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- (E)-3-(4-Fluorophenyl)acrylonitrile (CAS 24654-48-6)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com