Palonosetron Impurity 25 CAS 23357-47-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.23357-47-3
Molecular FormulaC11H12O2
Molecular Weight176.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Palonosetron Impurity 25 CAS 23357-47-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 176.21 g/mol gives Palonosetron Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Palonosetron Impurity 25 (CAS 23357-47-3) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12O2 and a molecular weight of 176.21 g/mol.

Structurally, Palonosetron Impurity 25 (C11H12O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 176.21 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H12O2
Molecular Weight176.21 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963

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