Agomelatine Impurity 16 CAS 6836-19-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.6836-19-7
Molecular FormulaC11H12O2
Molecular Weight176.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Agomelatine Impurity 16 CAS 6836-19-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 176.21 g/mol gives Agomelatine Impurity 16 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Agomelatine Impurity 16 (CAS 6836-19-7), a pharmacopoeial impurity reference standard (molecular formula C11H12O2, MW 176.21 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Agomelatine Impurity 16 (C11H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Agomelatine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H12O2
Molecular Weight176.21 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

Related Agomelatine Standards

Recommended Standards

Why CATO?