1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine CAS 477848-01-4
| CAS No. | 477848-01-4 |
| Molecular Formula | C15H15ClF3N3S |
| Molecular Weight | 361.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine.
1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine (CAS 477848-01-4) is a high-purity analytical reference standard with the molecular formula C15H15ClF3N3S and a molecular weight of 361.81 g/mol.
Structurally, 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine (C15H15ClF3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 361.81 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H15ClF3N3S |
| Molecular Weight | 361.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(3-Chloro-2-methylphenyl)-5-((pyrimidin-2-ylthio)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1416343-47-9)
- 1-(5-Chloro-2-methylphenyl)-5-((pyrimidin-2-ylthio)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1416346-35-4)
- 7-Chloro-4-(3,4-dimethoxyphenethyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326872-06-3)
- 7-Chloro-4-ethynyl-1,4-dihydro-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (CAS 1958012-17-3)
- 2-(5-Chloro-2-ethoxy-4-formylphenoxy)-N-phenethylacetamide (CAS 692267-44-0)
- 2-Chloro-3-(2-oxo-2-(pyrrolidin-1-yl)ethoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one (CAS 380476-01-7)
- 2-Chloro-5-(dimethylamino)-4-nitro-N-phenylthiophene-3-sulfonamide (CAS 62019-20-9)
- 2-Chloro-N-methyl-N-(4-phenoxyphenyl)quinazolin-4-amine (CAS 827031-00-5)
Recommended Standards
- Indomethacin-D4 (CAS 87377-08-0)
- Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate (CAS 1035404-17-1)
- Sunitinib Impurity 23 (CAS CATO-C4X-133323)
- ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate (CAS 1035404-19-3)
- (S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid (CAS 205812-08-4)
- 5-(1-Chloroethyl)-6-nitro-2H-1,3-benzodioxole (CAS 1308676-67-6)
- MEthyl 2-([(tert-butoxy)carbonyl](methyl)amino)-3-methylbutanoate (CAS 130994-86-4)
- N-(tert-Butoxycarbonyl)-S-butylhomocysteine (CAS 1396969-20-2)
- 6-Chloro-N4-propylpyrimidine-4,5-diamine (CAS 195252-56-3)
- NF 157 (CAS 104869-26-3)
- 6-Bromo-7-fluoro-1-methyl-1H-indole (CAS 936901-95-0)
- 4-{[(3-fluorophenyl)amino]methyl}piperidin-4-ol (CAS 1315577-18-4)
- 4-Acetyl-6-methoxypicolinic acid (CAS 1393584-25-2)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com