Amitriptyline N-Oxide Hydrochloride CAS 4290-60-2
| CAS No. | 4290-60-2 |
| Molecular Formula | C20H23NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Amitriptyline N-Oxide Hydrochloride (CAS 4290-60-2) is a high-purity analytical reference standard with the molecular formula C20H23NOHCl and a molecular weight of 329.87 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Amitriptyline N-Oxide Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H23NO HCl |
| Molecular Weight | 329.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amitriptyline Standards
- Amitriptyline EP Impurity D (CAS 1159-03-1)
- Amitriptyline EP Impurity F (CAS 1159-82-6)
- Amitriptyline EP Impurity A (CAS 1210-35-1)
- Amitriptyline Hydrochloride - Impurity F (Oxalate Salt) (CAS 1246833-15-7)
- Amitriptyline-13C3 Hydrochloride (CAS 1329837-86-6)
- Amitriptyline-d6 Hydrochloride (CAS 203645-63-0)
- Amitriptyline EP Impurity C-d3 HCl (CAS 203784-52-5)
- Amitriptyline EP Impurity E HCl (Mixture of Diastereomers) (CAS 26360-49-6(free base))
Recommended Standards
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- Sodium 2-(bis(2-(phosphonooxy)ethyl)amino)ethyl hydrogen phosphate (CAS 68171-29-9)
- 2-[(piperidin-4-yl)amino]acetic acid dihydrochloride (CAS 1082735-89-4)
- 2-phenylprop-2-en-1-amine hydrochloride (CAS 56132-76-4)
- 2-(4-Isopropylphenyl)-8-methylquinoline-4-carboxylic acid (CAS 438231-85-7)
- 4-Ethyl-1-methyl-3-(tert-pentyl)-1h-pyrazol-5-amine (CAS 1247616-69-8)
- N-(5-Amino-2-methoxyphenyl)-2-[2,4-di(tert-butyl)-phenoxy]acetamide (CAS 1020056-14-7)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
Why CATO?
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