Berberine Impurity 24 CAS 430433-40-2
| CAS No. | 430433-40-2 |
| Molecular Formula | C18H21NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Berberine Impurity 24 (CAS 430433-40-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H21NO4HCl and a molecular weight of 351.83 g/mol.
The molecular framework of Berberine Impurity 24 (C18H21NO4HCl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Berberine Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO4 HCl |
| Molecular Weight | 351.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Berberine Standards
- Berberine Impurity 33 (CAS 100101-07-3)
- Berberine Impurity 15 Chloride (CAS 1186107-72-1)
- Berberine Chloride hydrate (CAS 141433-60-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- Berberine Impurity 14 (CAS 2043361-62-0)
- Berberine (CAS 2086-83-1)
- Berberine Impurity 16 Chloride (CAS 2363741-22-2)
- Berberine Impurity 29 (CAS 2375597-30-9)
Recommended Standards
- Abiraterone Impurity N1 (CAS 2118-32-3)
- Ziprasidone EP Impurity A HCl (CAS 87691-88-1)
- Propafenone Impurity 28 (CAS CATO-C4X-132228)
- 5-Acetyl-3-bromo-2H-pyran-2-one (CAS 2092491-80-8)
- 2-(Pent-4-en-1-yl)tetrahydrofuran-2-ol (CAS 85362-51-2)
- N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide (CAS 925434-55-5)
- 2-(2-Benzoyl-6-chloro-1H-indol-3-yl)acetic acid (CAS 231292-09-4)
- Methyl 2-(4-chloro-1H-pyrrolo[3,2-c]pyridin-1-yl)acetate (CAS 494767-41-8)
- 1,2,3-Benzothiadiazole-5-carbonyl chloride 321309-32-4 benzo[d][1,2,3]thiadiazole-5-carbonyl chloride (CAS 321309-32-4)
- Semaglutide Impurity 6 (CAS 62-57-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com