Desoximetasone Impurity 6 CAS 432-54-2
| CAS No. | 432-54-2 |
| Molecular Formula | C22H31FO4 |
| Molecular Weight | 378.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 378.48 g/mol gives Desoximetasone Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Desoximetasone Impurity 6 (CAS 432-54-2, C22H31FO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Desoximetasone Impurity 6 (C22H31FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Desoximetasone Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H31FO4 |
| Molecular Weight | 378.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Desoximetasone Standards
- Desoximetasone Impurity 1 (CAS 2770242-92-5)
- Desoximetasone Impurity 5 (CAS 4306-57-4)
- Desoximetasone EP Impurity F (CAS 184899-80-7)
- Desoximetasone EP Impurity H (CAS 52092-65-6)
- Desoximetasone Impurity 3 (CAS 59796-52-0)
- Desoximetasone Impurity N3 (CAS 151265-33-7)
- Desoximetasone Impurity 2 (CAS CATO-C4X-16092)
- Desoximetasone Impurity 4 (CAS CATO-C4X-16094)
Recommended Standards
- 4,6-Bis((4-fluorophenyl)thio)-2-(methylthio)pyrimidine (CAS 860650-70-0)
- Fluorometholone Impurity 5 (CAS 378-36-9)
- 4-(4-Fluorophenyl)-2-[4-(octyloxy)phenyl]pyrimidine (CAS 477870-83-0)
- Cebranopadol(GRT6005) (CAS 863513-91-1)
- Fluorometholone Impurity 4 (CAS 110664-42-1)
- Ceritinib Impurity 3 (CAS CATO-C4X-10483)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
- 2-Amino-1-(p-tolyl)ethan-1-one (CAS 69872-37-3)
- (3-Hydroxyphenyl)(piperazin-1-yl)methanone hydrochloride (CAS 1240527-44-9)
- 2-((S)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-3,4-dihydro-2H-pyrrol-5-yl)-2-((S)-5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-ylidene)acetonitrile (CAS 105251-52-3)
- Ethyl 5-(2,2,2-trifluoroethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1340420-88-3)
- N-(2,2-dimethylthietan-3-yl)-3-(methylthio)acrylamide (CAS 1882845-72-8)
- 2,4-Dichlorophenyl methyl carbonate (CAS 5335-03-5)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com