Entacapone Impurity 26 CAS 672-13-9
| CAS No. | 672-13-9 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Entacapone Impurity 26 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Entacapone Impurity 26 (CAS 672-13-9, C8H8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Entacapone Impurity 26 (C8H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Entacapone Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Entacapone Standards
- Entacapone Impurity 30 (CAS 148-53-8)
- Entacapone EP Impurity C(Mixtures of tautomers) (CAS 116313-85-0)
- Entacapone impurity 38 (CAS CATO-C4X-162938)
- Entacapone Impurity N1 (CAS 15029-36-4)
- Entacapone Impurity 25 (CAS 6635-20-7)
- Entacapone Impurity 28 (CAS 2450-26-2)
- Entacapone Impurity 29 (CAS 2454-72-0)
- Entacapone Impurity 31 (CAS 80547-69-9)
Recommended Standards
- Droxidopa Impurity 2 (CAS 5707-55-1)
- Atomoxetine Hydrochloride EP Impurity E (CAS 17199-29-0)
- Levodopa Impurity 11 (CAS 85-43-8)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Mexiletine Impurity 1 (CAS 29238-40-2)
- Risdiplam impurity 5 (CAS CATO-C4X-30125)
- Baloxavir Marboxil Impurity 204 (CAS CATO-C4X-2108204)
- Vitamin A (CAS 68-26-8)
- Methyl 4-cyano-2,6-dimethylbenzoate (CAS 352278-82-1)
- 4-Bromo-3-chloro-5-methylbenzonitrile (CAS 1416351-73-9)
- 2-(tert-Butyl)-3-cyclopropoxypyridine-4-sulfonamide (CAS 1243441-16-8)
- Brivaracetam impurity 105 (CAS 2413102-60-8)
- 3-methyl-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one (CAS 112777-31-8)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com