Eltrombopag Impurity 48 CAS 43192-07-0
| CAS No. | 43192-07-0 |
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Eltrombopag Impurity 48 (C8H11NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Eltrombopag Impurity 48 (CAS 43192-07-0) is a certified pharmaceutical impurity reference standard with the molecular formula C8H11NO and a molecular weight of 137.18 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Eltrombopag Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 55 (CAS 13636-53-8)
- Eltrombopag Impurity 33 (CAS 16419-60-6)
- Eltrombopag Impurity 41 (CAS 17933-03-8)
- Eltrombopag Impurity 58 (CAS 5720-05-8)
- Eltrombopag impurity 145 (CAS 757889-55-7)
- Eltrombopag Impurity 158 (CAS CATO-C4X-1198158)
- Eltrombopag Impurity 31 (CAS 25487-66-5)
- Eltrombopag Impurity 40 (CAS 591-17-3)
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