Formoterol Impurity 23 CAS 43229-01-2
| CAS No. | 43229-01-2 |
| Molecular Formula | C15H12BrNO4 |
| Molecular Weight | 350.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 350.16 g/mol gives Formoterol Impurity 23 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Formoterol Impurity 23 (CAS 43229-01-2, C15H12BrNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Formoterol Impurity 23 (C15H12BrNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 350.16 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12BrNO4 |
| Molecular Weight | 350.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Formoterol Standards
- Formoterol impurity 142 (CAS CATO-C4X-1525142)
- Formoterol Impurity 69 (CAS 100865-09-6)
- Formoterol Impurity 28 (CAS 201677-59-0)
- Formoterol Impurity 59 (CAS 306966-56-3)
- Formoterol-d6(Mixture of Diastereomers) (CAS 1020719-45-2)
- Formoterol impurity 126 (CAS CATO-C4X-1525126)
- Formoterol impurity 127 (CAS 188690-82-6)
- Formoterol Impurity 54 (CAS 193761-53-4)
Recommended Standards
- Clonazepam impurity 10 (CAS CATO-C4X-140310)
- 1-[6,8-Dichloro-2-(trifluoromethyl)quinol-4yl]piperazine (CAS 1000339-48-9)
- Lorazepam impurity 9 (CAS CATO-C4X-10419)
- 1-(4-(4-Bromo-2-(trifluoromethyl)phenyl)piperidin-1-yl)ethanone (CAS 1422252-49-0)
- Flomoxef Impurity 32 (CAS CATO-C4X-138232)
- Lenvatinib Impurity 111 (CAS CATO-C4X-1140111)
- Timolol Impurity 23 (CAS CATO-C4X-149623)
- Ethyl 3-(3-methyl-1h-pyrazol-1-yl)-2-(methylamino)propanoate (CAS 1341055-21-7)
- Ethyl 2-({5-methoxy-4-[3-(trifluoromethyl)phenoxy]pyrimidin-2-yl}sulfanyl)acetate (CAS 338423-35-1)
- 3-Methyl-6-(methylthio)benzo[d]thiazol-2(3H)-imine methanesulfonate (CAS 2034157-54-3)
- 2-((4-Aminophenyl)amino)acetamide (CAS 57946-58-4)
- 4-(piperidin-1-yl)cyclohexan-1-amine (CAS 192323-89-0)
- (4-Iodo-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid (CAS 6715-88-4)
- Semaglutide Impurity 6 (CAS 62-57-7)
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