5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid CAS 433283-22-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid.

5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid (CAS 433283-22-8), molecular formula C11H8FNO2S and molecular weight 237.25 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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