Sumatriptan Impurity 6 HCl CAS 4357-96-4
| CAS No. | 4357-96-4 |
| Molecular Formula | C8H10N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sumatriptan Impurity 6 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sumatriptan Impurity 6 HCl (CAS 4357-96-4), a pharmacopoeial impurity reference standard (molecular formula C8H10N3O2SCl, MW 247.70 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sumatriptan Impurity 6 HCl (C8H10N3O2SCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H10N3O2S Cl |
| Molecular Weight | 247.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Sumatriptan Standards
- Sumatriptan-D6 (CAS 1020764-38-8)
- Sumatriptan D6 Format Salt (CAS 1020764-38-8(free base))
- Sumatriptan Carboxylic Acid Impurity (CAS 103628-44-0)
- Sumatriptan (CAS 103628-46-2)
- Sumatriptan Succinate (CAS 103628-48-4)
- Sumatriptan aminophenyl Impurity C05 (CAS 109903-35-7)
- Sumatriptan-D6 Succinate (CAS 1215621-31-0)
- Sumatriptan EP Impurity B-d3 (CAS 1346600-79-0)
Recommended Standards
- Edoxaban Impurity 73 (CAS 1057651-37-2)
- Lasmiditan Impurity 58 (CAS CATO-C4X-247858)
- Ketoprofen EP Impurity I (CAS 21288-34-6)
- Aziridin-1-yl(cyclohexyl)methanone (CAS 98223-95-1)
- 1-Iodoimidazo[1,5-a]pyridine (CAS 1422773-18-9)
- 4-Cyclohexanecarbonyl-N-[3-(1H-imidazol-1-yl)propyl]-1H-pyrrole-2-carboxamide (CAS 439096-72-7)
- (2-(6-Methoxypyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352537-36-0)
- 3-(3-Oxocyclopentyl)propanoic acid (CAS 34399-77-4)
- N-butylthiazol-2-amine (CAS 69212-65-3)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com