Edoxaban Impurity 73 CAS 1057651-37-2
| CAS No. | 1057651-37-2 |
| Molecular Formula | C22H32N2O5 |
| Molecular Weight | 404.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Edoxaban Impurity 73 (CAS 1057651-37-2, C22H32N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H32N2O5, Edoxaban Impurity 73 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 404.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Edoxaban Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H32N2O5 |
| Molecular Weight | 404.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Edoxaban Standards
- Edoxaban Impurity 72 (CAS 365998-34-1)
- Edoxaban Impurity 73 (CAS 365998-33-0)
- Edoxaban Impurity 13 (CAS 767625-11-6)
- Edoxaban Impurity 54 (CAS 482375-18-8)
- Edoxaban Impurity 3 (CAS 480452-37-7)
- Edoxaban Impurity 12 (CAS 480450-71-3)
- Edoxaban Impurity 75 (CAS 1255529-31-7)
- Edoxaban Impurity N5 (CAS 365997-36-0)
Recommended Standards
- 807-05-6 11-hydroxy-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrodispiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxolane-5',4''-[1,3]dioxolan]-3(2h)-one DTXSID50297903 (CAS 807-05-6)
- Salbutamol Impurity 173 (CAS CATO-C4X-1176173)
- tert-Butyl 3-((1-(2-(benzyloxy)-2-oxoethyl)piperidin-4-yl)oxy)azetidine-1-carboxylate (CAS 2566692-85-9)
- Hydrocortisone EP Impurity J (CAS 16463-74-4)
- Lenalidomide Impurity 65 HCl (CAS CATO-C4X-190365)
- Topiroxostat Impurity 48 (CAS 4329-75-3)
- Pemetrexed Impurity 21 (CAS 1001-19-0)
- 3-Benzyl-1-phenylpiperazine (CAS 885275-37-6)
- Olsalazine EP Impurity E (CAS CATO-C4X-18015)
- CAS 2222690-89-1 (CAS 2222690-89-1)
- [1-(Piperidin-1-ylmethyl)cyclopropyl]-amine dihydrochloride (CAS 1255717-66-8)
- 8-Methoxy-thiochroman-3-ylamine hydrochloride (CAS 178553-33-8)
- 2-Aminohexane-1,3-diol (CAS 50730-98-8)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
Why CATO?
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