4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-2-yl)pyrimidine CAS 439109-63-4
| CAS No. | 439109-63-4 |
| Molecular Formula | C22H16ClN3O |
| Molecular Weight | 373.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-2-yl)pyrimidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-2-yl)pyrimidine (CAS 439109-63-4) is a high-purity analytical reference standard with the molecular formula C22H16ClN3O and a molecular weight of 373.83 g/mol.
The molecular framework of 4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-2-yl)pyrimidine (C22H16ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3O |
| Molecular Weight | 373.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorophenyl Standards
- 1-(4-Chlorophenyl)-3-(4-(4-nitrophenyl)piperazin-1-yl)propan-1-one (CAS 477328-84-0)
- 2-(4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl)-N-(4-methylbenzyl)acetamide (CAS 478033-73-7)
- 4-{2-[(4-chlorophenyl)methoxy]phenyl}-2-(pyridin-4-yl)pyrimidine (CAS 439109-62-3)
- 4-Chlorophenyl 8-methyl-2-phenylquinoline-4-carboxylate (CAS 355421-40-8)
- N-(4-Chlorophenyl)-1,5-diphenyl-1H-pyrazole-4-carboxamide (CAS 477711-89-0)
- 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (CAS 545399-94-8)
- Methyl 1-(4-chlorophenyl)-6-oxo-4-(pyridin-2-ylsulfanyl)-1,6-dihydropyridazine-3-carboxylate (CAS 338405-50-8)
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Recommended Standards
- 4-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-(4-chlorophenyl)piperazine-1-carboxamide (CAS 340220-97-5)
- 3-Chloro-4-(diphenylamino)-6-phenyl-2H-pyran-2-one (CAS 70486-07-6)
- 3-((4-Chlorobenzyl)oxy)-5,6-diphenyl-1,2,4-triazine (CAS 866149-91-9)
- Carprofen EP Impurity F (CAS 71208-55-4)
- 3-(3-Chlorophenyl)-6-{[3-(2,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1040645-62-2)
- (S)-1-(5-bromo-2-fluorophenyl)ethan-1-amine hydrochloride (CAS 1228565-59-0)
- n-(4-Ethoxyphenyl)furan-2-carboxamide (CAS 60943-79-5)
- 4-Chloro-2-((4-(trifluoromethyl)benzyl)thio)pyridine (CAS 1346707-63-8)
- 1,3-Dioxa-8-azaspiro[4.5]Decan-2-one (CAS 1227465-63-5)
- N,N-Dimethyl-2-(4,5,6,7-tetrachloroisoindolin-2-yl)ethanamine (CAS 95467-71-3)
- Ivabradine Impurity 15 (CAS CATO-C4X-111915)
- 2-(3-aminooxolan-3-yl)acetic acid (CAS 1341575-20-9)
- 3-(2-(Tert-Butoxycarbonyl)-1,2,3,4-Tetrahydroisoquinolin-6-Yl)Propanoic Acid (CAS 1158756-02-5)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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