4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate CAS 545399-94-8
| CAS No. | 545399-94-8 |
| Molecular Formula | C18H12ClNO4S |
| Molecular Weight | 373.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate.
CATO supplies 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (CAS 545399-94-8), a certified reference material (molecular formula C18H12ClNO4S, MW 373.81 g/mol) for analytical method development and quality control.
4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (C18H12ClNO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClNO4S |
| Molecular Weight | 373.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-Chloro-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-2-phenylacetamide (CAS 565191-94-8)
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- 3-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-5-methylcyclohex-2-en-1-one (CAS 1024353-40-9)
- Dacomitinib Impurity 27 (CAS CATO-C4X-208627)
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- 2,4,5-Trimethyl-1-(pyridin-3-ylmethyl)-1H-pyrrole-3-carbaldehyde (CAS 1087611-41-3)
- Methyl 2-(4-(aminomethyl)-3-methylphenyl)acetate (CAS 2170478-35-8)
- all-trans 4-Keto Retinoic Acid-(9-methyl)-d3 (CAS 1346606-26-5)
- tert-Butyl[(3-ethoxyphenyl)methyl]amine (CAS 880803-97-4)
- N-tert-butyl-6-chloro-1-(trideuteriomethyl)pyrazolo[3,4-d]pyrimidin-4-amine (CAS 2570124-21-7)
- 2-[(4-fluorophenyl)methoxy]propanoic acid (CAS 220000-23-7)
- 2-Hydroxy-2-(pyrimidin-5-yl)acetic acid (CAS 1516304-94-1)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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