1,5-Difluoro-2-methoxy-3-nitrobenzene CAS 441-31-6
| CAS No. | 441-31-6 |
| Molecular Formula | C7H5F2NO3 |
| Molecular Weight | 189.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1,5-Difluoro-2-methoxy-3-nitrobenzene (CAS 441-31-6) is a high-purity analytical reference standard with the molecular formula C7H5F2NO3 and a molecular weight of 189.12 g/mol.
The molecular framework of 1,5-Difluoro-2-methoxy-3-nitrobenzene (C7H5F2NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 1,5-Difluoro-2-methoxy-3-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F2NO3 |
| Molecular Weight | 189.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 3,5-Difluoro-4-nitrobenzyl Alcohol (CAS 1123172-89-3)
- (2,5-Difluoro-4-nitrophenyl)methanol (CAS 1160474-68-9)
- 1,2-Difluoro-3-methoxy-5-nitrobenzene (CAS 1235492-43-9)
- 2,6-Difluoro-4-nitrobenzyl alcohol (CAS 1260811-86-6)
- (3,5-Difluoro-2-nitrophenyl)methanol (CAS 1378491-35-0)
- 1,3-Difluoro-2-methoxy-4-nitrobenzene (CAS 1393179-73-1)
- 1,5-Difluoro-2-methoxy-4-nitrobenzene (CAS 179011-39-3)
- (2,5-Difluoro-3-nitrophenyl)methanol (CAS 1803730-48-4)
Recommended Standards
- 1,3-Difluoro-5-methoxy-2-nitrobenzene (CAS 66684-62-6)
- 2,3-Difluoro-4-nitroanisole (CAS 66684-59-1)
- 1,2-Difluoro-4-methoxy-5-nitrobenzene (CAS 66684-64-8)
- 2,3-difluoro-6-nitroanisole (CAS 66684-65-9)
- {1-[(2-chlorophenyl)methyl]pyrrolidin-2-yl}methanol (CAS 1017479-63-8)
- 1-[4-(Ethylsulfonyl)-2-nitrophenyl]piperidine (CAS 942474-62-6)
- (2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone (CAS 2095393-15-8)
- 3-Methyl-2,4,6,7-tetrahydropyrano[4,3-c]pyrazole (CAS 1211498-13-3)
- Ethyl 5-((tert-butoxycarbonylamino)methyl)-1,2,4-oxadiazole-3-carboxylate (CAS 164029-34-9)
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- (E)-4-((4-((4-Carbamoyl-2-(3-morpholinopropoxy)-6-nitrophenyl)amino)but-2-en-1-yl)amino)-3-methoxy-5-nitrobenzamide (CAS 2138302-07-3)
- 3-Bromo-4-fluorobenzaldehyde (CAS 77771-02-9)
- Methyl 4-amino-1-(3-cyanopropyl)-1h-pyrrole-2-carboxylate (CAS 1249039-23-3)
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