Riluzole Impurity 25 CAS 442665-84-1
| CAS No. | 442665-84-1 |
| Molecular Formula | C10H7F3N2O2S |
| Molecular Weight | 276.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Riluzole Impurity 25 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Riluzole Impurity 25 (CAS 442665-84-1, C10H7F3N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Riluzole Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2O2S |
| Molecular Weight | 276.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Riluzole Standards
- Riluzole Impurity 7 (CAS 1456696-94-8)
- Riluzole Impurity 27 (CAS 2273706-77-5)
- Riluzole Impurity 26 (CAS CATO-C4X-200926)
- Riluzole Impurity 17 (CAS CATO-C4X-200917)
- Riluzole Impurity 14 (CAS CATO-C4X-200914)
- Riluzole Impurity 6 (CAS 179070-90-7)
- Riluzole Impurity 4 (CAS 144631-82-3)
- Riluzole-13C,15N2 (CAS 1215552-03-6)
Recommended Standards
- 890100-22-8 3-(3,5-Difluorobenzoyl)phenyl acetate DTXSID50641664 (CAS 890100-22-8)
- 5-((5-Formyl-2-methoxyphenoxy)methyl)furan-2-carboxylic acid (CAS 1018246-47-3)
- 890100-01-3 4-(2,6-Difluorobenzoyl)phenyl acetate DTXSID70641727 (CAS 890100-01-3)
- (2S,3R,4S,5R)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 10369-25-2)
- Neostigmine impurity 41 (CAS CATO-C4X-204241)
- Indometacin Impurity 46 (CAS CATO-C4X-147046)
- Clindamycin Phosphate Sulfoxide Impurity (CAS 1228573-90-7)
- Ethyl 4-amino-5-cyano-2-methyl-1H-pyrrole-3-carboxylate (CAS 129305-85-7)
- 1-((((2,5-Dioxopyrrolidin-1-yl)oxy)carbonyl)oxy)ethyl benzoate (CAS 918448-41-6)
- 4-[4-(Ethoxycarbonyl)tetrahydro-2H-pyran-4-yl]phenylboronic Acid Pinacol Ester (CAS 1423702-59-3)
- 1,2,4,5-Tetraisopropylbenzene (CAS 27322-46-9)
- N-tert-butyl-1-methyl-cyclopropanesulfonamide (CAS 669008-25-7)
- 4-Amino-N-(tert-butoxycarbonyl)-L-phenylalanine Methyl Ester (CAS 65615-90-9)
- Neuropeptide EI (human, mouse, rat) (CAS 125934-45-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com