ethyl 2-bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylate CAS 444326-49-2
| CAS No. | 444326-49-2 |
| Molecular Formula | C7H10BrF3N2O2 |
| Molecular Weight | 291.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ethyl 2-bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylate (CAS 444326-49-2) is a high-purity analytical reference standard with the molecular formula C7H10BrF3N2O2 and a molecular weight of 291.07 g/mol.
The molecular framework of ethyl 2-bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylate (C7H10BrF3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures ethyl 2-bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H10BrF3N2O2 |
| Molecular Weight | 291.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
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