2-((3-Cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2-(trifluoromethoxy)phenyl)acetamide CAS 488134-50-5
| CAS No. | 488134-50-5 |
| Molecular Formula | C23H19F3N4O2S2 |
| Molecular Weight | 504.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((3-Cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2-(trifluoromethoxy)phenyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 504.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-((3-Cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2-(trifluoromethoxy)phenyl)acetamide (CAS 488134-50-5) is a high-purity analytical reference standard with the molecular formula C23H19F3N4O2S2 and a molecular weight of 504.55 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-((3-Cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2-(trifluoromethoxy)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H19F3N4O2S2 |
| Molecular Weight | 504.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Cyano Standards
- (R)-4-cyano-N-(3-(cyclopropyl(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)methyl)phenyl)benzenesulfonamide (CAS 166335-16-6)
- 2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-(4-phenylthiazol-2-yl)acetamide (CAS 332859-73-1)
- 2,6-Bis[cyano(morpholin-4-yl)phenylmethyl]benzonitrile (CAS 400089-38-5)
- 2-((3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(5-phenyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 309745-18-4)
- N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-{[3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetamide (CAS 445383-39-1)
- 2-Cyano-3,11-dioxo-18�-oleana-1,12-dien-30-oic acid methyl ester (CAS 944832-18-2)
- N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-((3-cyano-6-(4-fluorophenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 488801-72-5)
- 2-((3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 496773-54-7)
Recommended Standards
- Fmoc-Gly-(Dmb)Gly-OH (CAS 848861-65-4)
- 3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 445382-88-7)
- Osimertinib Impurity 60 (CAS CATO-C4X-204560)
- Vonoprazan Impurity 175 (CAS CATO-C4X-1020175)
- (3R,4R,5S)-3-amino-4,5-dimethylpyrrolidin-2-one hydrochloride (CAS 2417777-79-6)
- 4-Pyrrolidin-3-yl-pyrimidin-2-ylamine dihydrochloride (CAS 1361114-71-7)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-methoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-75-2)
- 2-Methyl-1-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)propan-1-amine (CAS 1342036-01-4)
- (S)-Ethyl-5-(4-(benzyloxy)phenyl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate (CAS 1200041-07-1)
- 7-Nitrochroman-4-one (CAS 22528-79-6)
- 3',4-Difluoro-[1,1'-biphenyl]-3-amine (CAS 1214339-26-0)
- ditert-butyl 6-bromo-7-methyl-spiro[3,4-dihydro-1,8-naphthyridine-2,3'-pyrrolidine]-1,1'-dicarboxylate (CAS 2755893-16-2)
- Tert-butyl ((2s,4r)-6-azaspiro[3.4]Octan-2-yl)carbamate (CAS 2227197-82-0)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com