2-Fluoro-4-methylaniline, 97% CAS 452-80-2
| CAS No. | 452-80-2 |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Fluoro-4-methylaniline, 97% (C7H8FN) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Fluoro-4-methylaniline, 97% (CAS 452-80-2), a certified reference material (molecular formula C7H8FN, MW 125.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Fluoro-4-methylaniline, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-Fluoro-3,5-dimethylpyridine (CAS 111887-71-9)
- 5-Fluoro-2,3-dimethylpyridine (CAS 113209-99-7)
- 2-Fluoro-3,4-dimethylpyridine (CAS 1227570-87-7)
- 3-Fluoro-2,4-dimethylpyridine (CAS 1227575-02-1)
- 5-Fluoro-2,4-dimethylpyridine (CAS 1806569-94-7)
- 2-Fluoro-3-methylaniline (CAS 1978-33-2)
- 3-Fluoro-N-methylaniline (CAS 1978-37-6)
- 2-Fluoro-N-methylaniline (CAS 1978-38-7)
Recommended Standards
- 2-(Fluoromethyl)aniline (CAS 511230-96-9)
- 2-Fluoro-5-methylaniline (CAS 452-84-6)
- 2-(2-Fluoroethyl)pyridine (CAS 497914-02-0)
- 3-(Fluoromethyl)aniline (CAS 456-46-2)
- N-(2-(Dimethylamino)ethyl)-4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)-N-methylbenzenesulfonamide (CAS 107478-35-3)
- (2E)-N-(4-Fluoro-3-methylphenyl)-3-[4-(trifluoromethoxy)phenyl]prop-2-enamide (CAS 882082-47-5)
- 1-(2,5-Dimethylbenzenesulfonyl)piperazine (CAS 524711-33-9)
- (S)-4-(Allyloxy)-2-amino-4-oxobutanoic acid hydrochloride (CAS 123975-49-5)
- Dimethachlor-ethane sulfonic acid (ESA) sodium (CAS 1231710-75-0)
- 2-(2-Thienyl)-1,3-thiazole-4-carboxylic acid 2-(thiophen-2-yl)thiazole-4-carboxylic acid 24044-07-3 (CAS 24044-07-3)
- 6-Amino-5-fluoro-1-methylpyrimidine-2,4(1H,3H)-dione (CAS 250658-21-0)
- 2-(3-Fluoro-4-phenoxyphenyl)ethan-1-amine (CAS 910405-57-1)
- Methyl 3-(((tetrahydro-2H-thiopyran-2-yl)methyl)amino)acrylate (CAS 1704402-90-3)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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