2-Fluoro-5-methylaniline CAS 452-84-6
| CAS No. | 452-84-6 |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H8FN, 2-Fluoro-5-methylaniline contains a nitrile group, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 125.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Fluoro-5-methylaniline (CAS 452-84-6), a certified reference material (molecular formula C7H8FN, MW 125.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Fluoro-5-methylaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-Fluoro-3,5-dimethylpyridine (CAS 111887-71-9)
- 5-Fluoro-2,3-dimethylpyridine (CAS 113209-99-7)
- 2-Fluoro-3,4-dimethylpyridine (CAS 1227570-87-7)
- 3-Fluoro-2,4-dimethylpyridine (CAS 1227575-02-1)
- 5-Fluoro-2,4-dimethylpyridine (CAS 1806569-94-7)
- 2-Fluoro-3-methylaniline (CAS 1978-33-2)
- 3-Fluoro-N-methylaniline (CAS 1978-37-6)
- 2-Fluoro-N-methylaniline (CAS 1978-38-7)
Recommended Standards
- 2-Fluoro-4-methylaniline, 97% (CAS 452-80-2)
- 3-(Fluoromethyl)aniline (CAS 456-46-2)
- 2-(Fluoromethyl)aniline (CAS 511230-96-9)
- 3-Ethyl-5-fluoropyridine (CAS 2089319-08-2)
- 2-[3,5-di(trifluoromethyl)anilino]-3-methyl-4-(2-naphthyl)-1,3-thiazol-3-ium bromide (CAS 282539-01-9)
- Fmoc-Lys(palmitoyl)-OH (CAS 201004-46-8)
- Dimethylformamidium trifluoromethanesulfonate (CAS 705301-17-3)
- 4-(2,5-Dimethylthiophen-3-yl)-N-methylthiazol-2-amine (CAS 931626-97-0)
- 1-(2,2-Dimethylcyclohexyl)ethan-1-amine (CAS 1506318-25-7)
- (1R)-1-(3-nitrophenyl)propan-1-ol (CAS 286934-41-6)
- 4-Fluorophenyl 3-(trifluoromethyl)benzoate (CAS 218929-27-2)
- 7-Chlorofuro[2,3-c]quinolin-4(5H)-one (CAS 89972-50-9)
- 2-Ethoxy-1,3-dimethyl-1,3,2-diazaphospholidine 2-oxide (CAS 10026-27-4)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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